In about five to ten years, immunology has gone through a revolution. The critical role that immune cell metabolism plays in generating one immune response or another is being studied and understood. This new area of research is call immunometabolism. Immunometabolism: The Revolution Is Here You’ve no doubt heard or read in the news more than once about an increase in diseases relate to a poorly functioning immune system. From allergies and autoimmune diseases, to certain types of cancer. And of course you know, to a large extent, this growth is the price we pay for the way we eat, the way we live our lives. The good news is that the physiological mechanisms by which our lifestyles alter immune system function, for better or worse, are beginning to be discovered. This understanding can guide us beyond disease prevention.
New therapeutic tools
Are also being developed for their treatment. This is the whole story. In about five to ten years, immunology has gone through a revolution. The critical role that immune cell metabolism plays in generating one immune response or Argentina Mobile Number Database another is being studied and understood. This new area of research is called immunometabolism. And, thanks to it, we are moving beyond classical approaches based on immunosuppression to inhibit all responses, including those that generate pathology and the rest of the immune regulatory pathways. Consider and take advantage of the highly specific nature of the immune system. Immunometabolism: From Sprints to Marathons To understand what immunometabolism consists of, we need to remember how our bodies work when it comes to obtaining energy.
Of all energy substrates
Fat produces the greatest number of energy molecules. The second substrate for energy production is glucose burned in the presence of oxygen. The third way to obtain energy is glucose without oxygen. It is the substrate that produces Austria Phone Number List the least amount of energy. Energy production is now shifting from qualitative to quantitative efficiency. Instead, this means that the fastest way to produce energy is anaerobic glucose, followed by aerobic glucose, and finally fat. We see this more clearly on track and field: if I want to do a sprint because I need energy quickly. I will inject glucose without oxygen, even at the expense of producing the waste product lactate. If I’m facing a five-kilometer race, I’d be better off burning glucose with oxygen but if my goal is a marathon, then what I need is to generate energy for a longer period of time.
